Predictive parameters for imatinib failure in patients with chronic myeloid leukemia
نویسندگان
چکیده
منابع مشابه
Analysis of Expression Of SIRT1 Gene In Patients With Chronic Myeloid Leukemia Resistant To Imatinib Mesylate
Background: Chronic myeloid leukemia is a clonal myeloproliferative disease which is characterized by bcr/abl translocation. With the emergence of tyrosine kinase inhibitors such as imatinib mesylate, significant improvement has been made in treatment of this disease. However, drug resistance against this medicine is still an obstacle. SIRT1 is a gene with deacetylase activity which has been de...
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ژورنال
عنوان ژورنال: Hematology
سال: 2017
ISSN: 1024-5332,1607-8454
DOI: 10.1080/10245332.2017.1302179